Prospective Multi-omics Observational Study of Gynecological Rare Pathological Tumors

Beobachtungsstudie

Phase nicht angegeben

Sponsor: RenJi Hospital

Zuletzt aktualisiert: 14. August 2023
Hinweis - Die Informationen stammen aus öffentlichen Registern und spiegeln möglicherweise nicht die Echtzeitänderungen am lokalen Studienzentrum wider.

The goal of this observational study is to draw the characteristic maps of genomics, transcriptome, proteomics, metabolomics, etc. in 600 patients with gynecological rare pathological types of malignant tumors. Then it is planned to explore the molecular mechanism and find some new targets for diagnosis and treatment, and design and establish the database system of the above rare tumors.

Behandlungskategorie

Erforderliche Mutationen

Keine

Studie gestartet

16. August 2023

Zuletzt vom Sponsor aktualisiert

14. August 2023

Voraussichtlicher Abschluss

1. Mai 2028

Studienkontakt

Eignung

Einschlusskriterien

* 1)Pathological diagnosis: clear cell carcinoma (ovary, uterus), nerve small-cell carcinoma (ovary, uterus), carcinosarcoma or sarcoma (ovary, uterus), cervical gastric adenocarcinoma, ovarian germ cell tumor, ovarian sex cord stromal tumor, trophoblastic tumor, perivascular epithelioid cell tumor (PECOMA) and other rare gynecological tumors; 2)Received pathological results from tumor surgery; 3)The patient voluntarily participated in this research project with good compliance and was able to complete the enrollment according to the experimental requirements; 4)Sign the informed consent form and consent to the collection and use of their data, and consent to genomics, transcriptome and other tests.

Ausschlusskriterien

* 1)Patients with malignant tumors in other parts of the body; 2)Suffering from uncontrollable neurological diseases, psychiatric diseases, or psychiatric disorders; 3)Poor compliance and inability to cooperate and describe treatment responders.

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Design-Details

ZuteilungN/A

InterventionsmodellN/A

MaskierungN/A

Anzahl der Teilnehmer600

Arme & Interventionen

Arme

Interventionen

Keine Interventionen verfügbar.

Ergebnismessungen

Primäre Ergebnismessungen

Multi-omics feature mapAugust 2023 to May 2028

Draw the characteristic maps of imaging omics, genomics, transcriptome, proteomics, pathological omics, metabolomics, etc. of patients with gynecological rare pathological types of malignant tumors, and explore the molecular mechanism thus finding some new targets for diagnosis and treatment.

Database systemAugust 2023 to May 2028

Design and establish the database system of the above gynecological rare pathological types of tumors.

Sekundäre Ergebnismessungen

Correlation analysisAugust 2023 to May 2028

Integrate the characteristic maps of imaging omics, genomics, transcriptome, proteomics, pathological omics, metabonomics, etc. to study their possible relevance.

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