Study of BMS-986497 (ORM-6151) as a Monotherapy, in Double and Triple Combination With Azacitidine and Venetoclax in Participants With Relapsed or Refractory Acute Myeloid Leukemia or Myelodysplastic Syndrome (NCT06419634)
Study of BMS-986497 (ORM-6151) as a Monotherapy, in Double and Triple Combination With Azacitidine and Venetoclax in Participants With Relapsed or Refractory Acute Myeloid Leukemia or Myelodysplastic Syndrome
Interventionsstudie
Phase 1
Northwestern Memorial Hospital
Sponsor: Bristol Myers Squibb
Zuletzt aktualisiert: 30. Oktober 2025 Hinweis - Die Informationen stammen aus öffentlichen Registern und spiegeln möglicherweise nicht die Echtzeitänderungen am lokalen Studienzentrum wider.
The purpose of this study is to assess the safety, tolerability, drug levels, drug efficacy and determine the recommended dose of BMS-986497 as a monotherapy, in double combination with Azacitidine and in triple combination with Azacitidine and Venetoclax in participants with relapsed or refractory acute myeloid leukemia (AML) or myelodysplastic syndrome (MDS).
Behandlungskategorie
Andere Medikamente, Zielgerichtete Therapie
Erforderliche Mutationen
Keine
Studie gestartet
29. Mai 2024
Zuletzt vom Sponsor aktualisiert
30. Oktober 2025
Voraussichtlicher Abschluss
1. Februar 2027
Studienkontakt
Name:BMS Study Connect Contact Center www.BMSStudyConnect.com