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The aim of the study is to identify predictive factors related to the prognosis of patients with liver disease of dysmetabolic origin: Metabolic-Associated Steatotic Liver Disease and Metabolic-Associated Steatohepatitis (MASLD/MASH). Specifically, the aim is to identify markers that can predict individuals who will later require a liver transplant or develop hepatocellular carcinoma.
Calculate the incidence of liver transplantation and the occurrence of HCC for this disease.
Objective response rate in patients with HCC or those requiring liver transplantation, measured using RECIST 1.1 criteria.
Cases of liver decompensation, major adverse cardiovascular events (MACE), extrahepatic tumors, and liver transplantation, along with their time of onset.
Positive response to dietetic and drug therapies is measured by glycated hemoglobin levels.
Positive response to dietetic and pharmacological therapies is measured by weight loss.
Positive response to dietetic and pharmacological therapies is measured by biochemical parameters (Aspartate amino transferase, Alanina amino transferase).